Sometimes PGs get a little disoriented when bring the ball up the court with another guard. The fact that there are another two players off to his side as well as a defender in front of him creates a sense of crowdedness. Good ball handlers should not be phased by this because they are pulling defenders up and away from the basket while setting up entry passes and pressure release action.
We have all sort of ways in our offense to exploit this situation which have been described previously in other post but one thing that the guards can do is run a 'cross' where the ball handler just waves or pushes the non-ball handler to his side while dribbling the open or wide side of the court. It is a simple action but effective to do every once in a while. The non-ball handler can just loop to the ball handler's side of the court or he can run a blur cut right in front of the ball handler to make it look like more of a screening type of action.